**Core Concept**
The question is testing the knowledge of NSAIDs, specifically their pediatric use and safety profiles. The correct answer involves a specific NSAID that has been approved for use in children, taking into account its efficacy and safety in this population.
**Why the Correct Answer is Right**
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that has been approved for use in children for the treatment of juvenile rheumatoid arthritis. Its approval in children is based on studies demonstrating its efficacy and safety in this population. Diclofenac works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins, leading to a reduction in inflammation and pain.
**Why Each Wrong Option is Incorrect**
* **Option A:** Ibuprofen is commonly used in children for fever reduction and pain management, but it is not specifically approved for use in children with juvenile rheumatoid arthritis.
* **Option B:** Naproxen is an NSAID that is used to treat pain, inflammation, and fever in adults, but it is not approved for use in children.
* **Option C:** Ketorolac is an NSAID that is used to treat moderate to severe pain, but it is not approved for use in children.
**Clinical Pearl / High-Yield Fact**
When using NSAIDs in children, it's essential to weigh the benefits against the risks, including gastrointestinal side effects and potential effects on renal function. Always follow the recommended dosing and monitoring guidelines.
**Correct Answer:** C. Diclofenac.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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