Appropriate therapy with antiretroviral agents results in a syndrome characterized by an increased inflammatory response from the recovered immune system to subclinical oppounistic infection. What is this syndrome called as?
Correct Answer: Immune reconstitution inflammatory syndrome
Description: Immune reconstitution inflammatory syndrome (IRIS)- characterized by increased inflammatory response, subclinical oppounistic infections. common in patients with severe CD4 + T-lymphocyte depletion There is fever & worsening of clinical manifestations of oppounistic infection or new manifestations (e.g., enlargement of lymph nodes, pulmonary infiltrates), typically within the 1st few weeks after initiation of antiretroviral therapy.
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