Medical MCQ-Apparant volume of distribution of a drug less than 5 liters implies that the drug is predominantly in which of the following compament?

Apparant volume of distribution of a drug less than 5 liters implies that the drug is predominantly in which of the following compament?

Extracellular fluid

Total body water

Intracellular fluid

Intravascular fluid

Question Category:

Pharmacology

Correct Answer:

Extracellular fluid

Description:

Ans is 'a' i.e., Extracellular fluido A drug with high volume of distribution has more concentration in tissue and less in plasma.o A drug with low volume of distribution has concentration only in plasma (intravascular)Relationship between volume of distribution and extent of distributionVd (L)% body weightExtent of distribution< 57only in plasma5-207-28In extracellular fluid20-4028-56In total body water>40>56In deep tissues; bound to peripheral tissues

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