Apoptosis can occur by change in hormone levels in the ovarian cycle. When there is no feilization of the ovum, the endometrial cells die because :
Correct Answer: The involution of corpus luteum causes estradiol and progesterone levels to fall dramatically
Description: Ans. is a i.e. The involutlon of corpus luteum causea estradlol and progesterone levels to fall dramatlcally "The withdrawl of estrogen and progesterone initiates impoant endometrial events, vasoconstriction, the process of apoptosis, fissue loss and tinally menstruation." In the first half of the secretory phase, acid phosphatase and potent lytic enzymes are confined to lysosomes. Their release is inhibited by progesterone stabilisation of the lysosomal membranes. With the involution of corpus luteum, levels of estrogen and progesterone fall, the lysosomalmembranes are not maintained and enzymes are released which cause apoptosis of the endometrial cells.
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now