**Core Concept**
Apolipoproteins are proteins that bind to lipids to form lipoproteins, which are essential for lipid transport and metabolism in the body. Certain apolipoproteins act as enzyme activators, modifying the activity of enzymes involved in lipid metabolism.
**Why the Correct Answer is Right**
Apolipoprotein A-I (ApoA-I) is an enzyme activator that activates lecithin-cholesterol acyltransferase (LCAT), which converts unesterified cholesterol into cholesteryl ester. This process is crucial for the formation of high-density lipoprotein (HDL) and the efflux of excess cholesterol from peripheral tissues to the liver for excretion. ApoA-I also activates other enzymes involved in lipid metabolism, such as phospholipid transfer protein (PLTP).
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not a recognized apolipoprotein that acts as an enzyme activator.
**Option B:** This option is not a correct answer; however, the specific apolipoprotein is not provided here.
**Option C:** This option is not a recognized apolipoprotein that acts as an enzyme activator.
**Clinical Pearl / High-Yield Fact**
Apolipoproteins play a crucial role in lipid metabolism, and dysregulation of these proteins can lead to various lipid disorders, such as hyperlipidemia and atherosclerosis.
**Correct Answer: A. Apolipoprotein A-I (ApoA-I)**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.