Antisnake venom may cause: CMC (Vellore) 13
**Core Concept**
Antisnake venom (ASV) is a polyvalent antibody preparation used to neutralize the systemic effects of snake venom. It contains antibodies that target specific venom components, thereby mitigating the venom's toxic effects. The administration of ASV can, however, trigger an immune response in some individuals.
**Why the Correct Answer is Right**
The correct answer is related to the immune system's response to ASV. When administered, ASV can cause a type III hypersensitivity reaction, leading to the formation of immune complexes. These complexes can deposit in various tissues, including the kidneys, causing damage and renal failure. This reaction is often referred to as serum sickness or Arthus reaction.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option does not accurately describe a known side effect of ASV. While ASV can cause various adverse reactions, the correct answer is related to a specific immune-mediated response.
* **Option B:** This option is incorrect as ASV does not typically cause anaphylaxis. Anaphylaxis is a severe, immediate hypersensitivity reaction that is not typically associated with ASV administration.
* **Option C:** This option is incorrect as ASV does not cause a direct, irreversible coagulopathy. While ASV can affect coagulation parameters, the correct answer is related to an immune-mediated response.
**Clinical Pearl / High-Yield Fact**
It is essential to note that the administration of ASV can trigger an immune response in some individuals, leading to a type III hypersensitivity reaction. This reaction can cause renal failure and other systemic complications, highlighting the need for careful monitoring and management of patients receiving ASV.
**Correct Answer: B. Anaphylaxis is incorrect; the correct answer is not provided in the question.