## **Core Concept**
The question tests the mechanism of action of various antihelminthic drugs. Antihelminthic drugs work by either killing the parasites or inhibiting their growth and reproduction. The mechanism of action can vary among different classes of drugs.
## **Why the Correct Answer is Right**
The correct answer, , acts by producing flaccid paralysis of the worm. This drug works by blocking nicotinic acetylcholine receptors on the worm's muscle cells, leading to a flaccid paralysis. This mechanism is specific to certain antihelminthic drugs.
## **Why Each Wrong Option is Incorrect**
* **Option A:** typically works by inducing spastic paralysis of the worm, not flaccid paralysis. It increases the release of acetylcholine and also blocks the action of cholinesterase, leading to an accumulation of acetylcholine and spastic paralysis.
* **Option B:** works by disrupting microtubule function in the parasites, ultimately leading to their death. It does not act by producing paralysis.
* **Option D:** acts by interfering with the glucose uptake by the parasite, leading to depletion of glycogen stores and ultimately causing the death of the parasite. It does not produce paralysis.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that different antihelminthic drugs have distinct mechanisms of action. For example, is known for causing flaccid paralysis, whereas others like cause spastic paralysis. Understanding these mechanisms can help in choosing the right drug for a particular type of parasitic infection.
## **Correct Answer:** . Pyrantel
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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