**Core Concept:** Glaucoma is a group of eye conditions characterized by elevated intraocular pressure (IOP), which can damage the optic nerve and lead to vision loss or blindness. Antiglaucoma medications are used to lower IOP and prevent further damage. In infants, the drug safety profile is different due to immature organs and physiological differences.

**Why the Correct Answer is Right:** In infants, the most critical aspect to consider is their immature renal function. Most antiglaucoma medications are primarily eliminated by the kidneys, which can lead to accumulation of the drug and potential toxicity. In this case, **D** is the correct answer.

**Why Each Wrong Option is Incorrect:**

A. **Option A (Timolol):** Timolol is a beta-blocker that can cause bradycardia, hypotension, and respiratory depression in infants, leading to serious adverse effects.

B. **Option B (Brimonidine):** Brimonidine is an alpha-2 agonist that can cause systemic effects like hypotension, bradycardia, and respiratory depression, especially in infants due to their immature cardiovascular system.

C. **Option C (Dorzolamide):** Dorzolamide is a carbonic anhydrase inhibitor that can cause systemic side effects like hypotension and bradycardia, especially in infants due to their immature cardiovascular system.

**Clinical Pearl:** It is crucial to consider the age-specific pharmacokinetics and pharmacodynamics when selecting medications for infants. Always consult a pediatrician or a neonatologist while prescribing any medication to an infant to avoid potential adverse events.

**Correct Answer:** D (Dorzolamide)