Antiglaidin antibodies are seen in?
Correct Answer: Celiac disease
Description: Ans. is 'c' i.e., Celiac disease Diagnosis of Celiac disease* The definitive diagnosis is based on histopathologicalfindings which show :i) Villous atrophy and Crypt hyperplasia with decrease in villus : crypt ratio.ii) Loss of microvilli brush border.iii) Inflammatory cells are present in lamina propria : plasma cells, macrophages, lymphocytes, eosinophils and mast cells.iv) One of the characteristic feature is that overall mucosal thickness remains same (as villous atrophy is compensated by crypt hyperplasia).v) Mainly proximal intestine is involved.* Other characteristic diagnostic finding is symptom resolution on gluten free diet.* The most sensitive non-invasive serological tests are the presence of IgA antibodies to tissue transglutaminase or IgA/ IgG antibodies to deaminatedgliadin. Anti-endomysial antibodies are highly specific but less sensitive.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now