Anticoagulant effect of warfarin is increased by all of the following except-
Correct Answer: Phytonadione
Description: Ans. is 'b' i.e., Phytonadione o Warfarin shows a number of drug interactions and requires dose adjustment :? 1) Enzyme inducers (phenobarbitone, rifampicin, phenytoin, griseofulvin etc) and oral contraceptives (increase clotting factors) decrease the effect and hence require increase in dose of warfarin. 2) Drugs that increase the effect of warfarin and require dose reduction are enzyme inhibitors (cimetidine, erythromycin, cotrimoxazole, disulfiram, isoniazid, metronidazole, azoles, allopurinol), cephalosporins (cefamendole, cefoperazone, moxalactam), phenylbutazone, amiodarone, sulfinpyrazone, acute alcohol intake, loop diuretics and valproate.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now