Medicine Anti Topoisomerase I (Scl-70), anti-RNA polymerase III positivity is classically seen with: A Limited cutaneous sclerosis B Diffuse cutaneous sclerosis C CREST syndrome D SSc sine scleroderma 💡 Explanation Anti Topoisomerase I (Scl-70), anti-RNA polymerase III positivity is classically seen with: ✓ Correct Answer: B. Diffuse cutaneous sclerosis