Thyroid storm is an extreme form of thyrotoxicosis. The drugs used in thyroid storm are: Propanolol to control severe cardiovascular manifestations. It is life saving drug in thyroid storm and is DOC. CCBs like Diltiazem are used, if beta-blockers are C/I (as in asthmatics). Propylthiouracil is used to reduce the synthesis of thyroid hormones. It is anti thyroid DOC for thyroid storm. Hydrocoisone is used to protect the patient against shock.