Okay, let's tackle this question about Anti-Müllerian Hormone (AMH). The user wants a detailed explanation for a medical student preparing for exams like NEET PG or USMLE. First, I need to recall where AMH is secreted from. AMH is a glycoprotein hormone involved in sexual differentiation.

In males, during fetal development, the testes secrete AMH from Sertoli cells. This causes the regression of Müllerian ducts, which would otherwise develop into female reproductive structures. In females, AMH is also produced, but by the granulosa cells of the ovarian follicles, especially the small growing ones. However, the question is about the source, so the primary answer is Sertoli cells in the testes.

Now, the incorrect options might include other cell types. Let's think about the options. Common distractors could be Leydig cells (which produce testosterone), granulosa cells (though female, they do produce AMH in some contexts), theca cells, or maybe even placental cells. Each of these needs a brief explanation of why they're wrong. For example, Leydig cells are involved in testosterone production, not AMH. Theca cells are part of ovarian follicles but don't secrete AMH. Granulosa cells in females do secrete AMH, but the question is about the primary source. Wait, but in males, it's Sertoli cells. The question doesn't specify male or female, so the primary source is Sertoli cells in testes.

The clinical pearl here is that AMH is used as a biomarker for ovarian reserve in women, but its origin is in Sertoli cells. Also, in males, it's crucial for Müllerian duct regression. So the correct answer is Sertoli cells. The options need to be labeled A to D, but the user didn't provide them. So I'll have to refer to the options as A, B, C, D in the explanation. For each wrong option, explain why they're not the primary source. For example, if an option is Leydig cells, explain they produce testosterone. If another is granulosa cells, note they produce AMH in females but the primary source is Sertoli cells. The key is to clarify the primary source regardless of sex, which is Sertoli cells in testes.

**Core Concept**
Anti-Müllerian hormone (AMH) is a glycoprotein hormone critical for sexual differentiation in both males and females. In **males**, it is secreted by **Sertoli cells** in the testes during fetal development to regress Müllerian ducts. In **females**, granulosa cells of ovarian follicles secrete AMH, which regulates follicular recruitment and serves as a biomarker for ovarian reserve.

**Why the Correct Answer is Right**
The correct answer is **Sertoli cells in the testes**. During embryogenesis, Sertoli cells produce AMH to inhibit the development of Müllerian ducts into female reproductive structures (e.g., uterus, fallopian tubes). In postnatal males, AMH levels decline. In females, granulosa cells also produce AMH, but the question tests the **primary source** of AMH secretion, which is **Sertoli cells** in the testes. This distinguishes AMH from

✓ Correct Answer: C. Sertoli cells