Pharmacology Angiotensin converting enzyme inhibitors when used for a long time in patients with hypertension, cause: A Rightward shift in renal pressure-natriuresis curve B Reduction in filtration fraction C Significant increase in heart rate D No change in compliance of large arteries 💡 Explanation Angiotensin converting enzyme inhibitors when used for a long time in patients with hypertension, cause: ✓ Correct Answer: B. Reduction in filtration fraction