Angel dust is: NEET 13
## **Core Concept**
Angel dust, also known by its chemical name **phencyclidine (PCP)**, is a dissociative anesthetic that was originally developed for medical use in the 1950s. It has a high potential for abuse and is known for its hallucinogenic effects. PCP acts on the central nervous system and can induce a range of psychological and physiological symptoms.
## **Why the Correct Answer is Right**
The correct answer, **phencyclidine (PCP)**, is right because PCP is commonly referred to as angel dust due to its appearance as a white crystalline powder. It has a mechanism of action that involves the blockade of **N-methyl-D-aspartate (NMDA) receptors**, which are a subtype of glutamate receptors. By blocking these receptors, PCP disrupts the normal functioning of glutamate, a major excitatory neurotransmitter in the brain, leading to its dissociative and hallucinogenic effects.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because it does not correspond to phencyclidine (PCP).
- **Option B:** This option is incorrect because it does not correspond to phencyclidine (PCP).
- **Option D:** This option is incorrect because it does not correspond to phencyclidine (PCP).
## **Clinical Pearl / High-Yield Fact**
A key clinical pearl to remember is that **PCP (angel dust) can cause a range of systemic effects**, including tachycardia, hypertension, and respiratory distress, in addition to its psychological effects like hallucinations, dissociation, and potential for violent behavior. Clinicians should be aware of its potential for abuse and its challenging management in acute intoxication.
## **Correct Answer:** .