An old man, Om Prakash presented with anorexia, weakness, and paraesthesia. On further investigation, his hemoglobin came out to be 5.8 g% and the peripheral smear showed the presence of macrocytes and neutrophils having hypersegmented nuclei. His tendon reflexes also were sluggish. Endoscopy revealed atrophic gastritis. Deficiency of which of the following factors can lead to such a clinical situation?
Correct Answer: Vitamin B12
Description: Diagnosis of the patient is pernicious anemia. Factors favouring this diagnosis are:
Megaloblastic anemia.
Demyelination (decreased tendon reflexes)
Atrophic gastritis
So, he would require B12 supplementation.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now