An obese woman with type 2 diabetes and hypeension is diagnosed with endometriod type of endometrial carcinoma. Most probable gene defect expected in this condition is:
Correct Answer: PTEN
Description: Types of Endometrial cancer: Type 1(Endometroid type) Type 2(Serous,clear ,type) Associated with PTEN gene mutations Good prognosis Estrogen dependent Pre - invasive lesions Develops in obese women Associated with P-53 gene mutations Poor prognosis Not estrogen dependent Develops in thin women
Category:
Gynaecology & Obstetrics
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