Microbiology An idiotype is characterized by A Determinant exposed after papain cleavage to an F(ab')2 fragment B Determinant from one clone of cells and probably located close to the antigenbinding site of the immunoglobulin C Determinant inherited in a Mendelian fashion and recognized by crossimmunization of individuals in a species D Heavy-chain determinant recognized by heterologous antisera π‘ Explanation An idiotype is characterized by β Correct Answer: B. Determinant from one clone of cells and probably located close to the antigenbinding site of the immunoglobulin