Gynaecology & Obstetrics An HIV positive, 36 years old female on A councils. Which of the following 1st trimester markers of Down Syndrome would be affected by? A B-hcg B PAPP-A C NT D All of the above 💡 Explanation An HIV positive, 36 years old female on A councils. Which of the following 1st trimester markers of Down Syndrome would be affected by? ✓ Correct Answer: A. B-hcg