An AIDS patient complains of headaches and disorientation. A clinical diagnosis of Toxoplasma encephalitis is made and Toxoplasma cysts were observed in a brain section. Which one of the following antibody results would be most likely in this patient?
Correct Answer: IgM nonreactive, IgG reactive (low titre)
Description: (B) IgM nonreactive, IgG reactive (low titre) # One of the leading causes of death among AIDS patients is central nervous system Toxoplasmosis.> Toxoplasma infection is a result of reactivation of old or preexisting toxoplasmosis.> Occasionally; the infection may be acquired by needle sharing.> Because the disease is a reactivation of old or preexisting toxoplasmosis, routine quantitative tests for IgM antibody are usually negative and IgG titers are low (<1:256, IFA).> More sophisticated methods, such as IgM capture or IgG avidity, may reveal an acute response.
Category:
Microbiology
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