An 80-year-old microbiologist has a cerebral infarction. His speech is limited to expletives, he cannot write but does respond to questions by shaking his head, and he has lower facial weakness on the right side. The lesion is most likely in the:

Correct Answer: Left frontal lobe.
Description: Lower facial weakness is a localizing neighborhood sign. The Broca speech area is located in the posterior pa of the inferior frontal gyrus (Brodmann areas 44 and 45). Wernicke's speech area is intact as comprehension is intact.
Category: Anatomy
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