Presence of vomiting, lethargy, dehydration, hyponatremia, hyperkalemia, hypoglycemia and shock in this eight-year-old male infant suggest a diagnosis of neonatal adrenal insufficiency/crisis. Congenital Adrenal Hyperplasia is the most prevalent cause of adrenal insufficiency in neonates (typically 7-14 days post delivery) and the single best answer amongst the options provided, Clinical features of CAH (21 hydroxylase deficiency)Symptoms of classical CAH due to 21 hydroxylase deficiency are:Clinical: Lethargy, vomiting, Anorexia, weight loss, dehydration, hypotension, shock Mineralocorticoid deficiency: Hyponatremia, hyperkalemia, hypotension Cortisol deficiency: Hypoglycemia, Hyperpigmentation of areolar and scrotal areas in males and genital creases in females (due to ↑ ACTH secretion) Excess AndrogenMales: Phenotypically normal for some years, precocious puberty Females: Virilization (female pseudohermaphrodite)