Amyloidosis is most commonly seen in ?
Correct Answer: Type H DM
Description: Ans. is 'c' i.e., Type II DMo The two best examples of localized amyloidosis are Alzheimer's disease and type 2 diabetes mellitus.o Localized amyloid deposition results from the production of a unique polypeptide, which contains an amyloidogenicsequence and is capable of forming a beta-pleated sheet structure necessary for these deposits to aggregate. o In type 2 diabetes it is the islet amyloid polypeptide (IAPP) also known as amylin.o In Alzheimer's the unique peptide is the beta-amyloid protein (A beta).
Category:
Pathology
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