Which of the following statements are True /False? A. Listeria monocytogenes is a food borne pathogen B. Humans are probably accidental hosts for this microorganism C. Case-fatality rate of listeria meningitis is repoed to be 15-26% D. Granulomatosis infantiseptica is an overwhelming listerial fetal infection with miliary micro abscesses and granulomas E. Adults should receive IV ampicillin at high doses (2grams every 4hours)
**Question:** Which of the following statements are True /False? A. Listeria monocytogenes is a food borne pathogen B. Humans are probably accidental hosts for this microorganism C. Case-fatality rate of listeria meningitis is reported to be 15-26% D. Granulomatosis infantiseptica is an overwhelming listerial fetal infection with miliary micro abscesses and granulomas E. Adults should receive IV ampicillin at high doses (2grams every 4hours)
A. Listeria monocytogenes is a food borne pathogen
**Core Concept:** Listeria monocytogenes is a Gram-positive, facultatively anaerobic, rod-shaped bacterium that can cause severe infections in humans, particularly in immunocompromised individuals, newborns, and pregnant women. These infections are known as listeriosis or Listeriosis.
**Why the Correct Answer is Right:** Statement A is true because Listeria monocytogenes is known to cause foodborne infections, particularly in contaminated food products like unpasteurized milk, soft cheeses, and undercooked meats. Ingestion of these foods can lead to listeriosis, which presents with varied clinical manifestations, including meningitis, sepsis, and abortion.
B. Humans are probably accidental hosts for this microorganism
**Core Concept:** Humans are considered accidental hosts for Listeria monocytogenes as the bacteria typically enter the human body via ingestion of contaminated food products. Listeria monocytogenes is not naturally present in humans but can cause infections when consumed in contaminated food items.
**Why the Correct Answer is Right:** Statement B is true because Listeria monocytogenes is not a naturally occurring human pathogen. Its presence in humans is due to the consumption of contaminated food products, such as unpasteurized milk, soft cheeses, and undercooked meats. Ingestion of these foods allows Listeria monocytogenes to enter the human body and cause listeriosis.
C. Case-fatality rate of listeriosis is 15-26%
**Core Concept:** Listeriosis can be a severe and life-threatening infection, particularly in high-risk individuals like immunocompromised patients, newborns, and pregnant women. The case-fatality rate for listeriosis ranges from 15% to 26%.
**Why the Correct Answer is Right:** Statement C is true because listeriosis can lead to severe complications, particularly in high-risk individuals. The case-fatality rate for listeriosis falls within the range of 15% to 26%. This highlights the importance of prompt diagnosis and appropriate treatment in reducing mortality rates.
D. Granulomatosis infantis is an overwhelming fetal infection with micro abscesses and granulomas
**Core Concept:** Granulomatosis infantis is an outdated term for listeriosis, particularly in pregnant women. The term granulomatosis is incorrect, while the clinical manifestations of Listeria monocyt