Ammonia is toxic to the brain because it leads to depletion of which substrate?
Correct Answer: Alpha ketoglutarate
Description: Ans. B. Alpha ketoglutarateAmmonia reacts with Glutamate to form Glutamine. The Glutamate is formed from alpha keto glutarate an intermediate of TCA Cycle. So alpha ketoglutarate is depleted.
Category:
Biochemistry
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