Which of the following correlates well to overcoming of limiting amino acids in diet: March 2013
**Core Concept**
The concept of overcoming limiting amino acids in the diet is related to the nitrogen balance and protein synthesis in the body. Limiting amino acids refer to the essential amino acids that are present in insufficient amounts in the diet, which can lead to a negative nitrogen balance and decreased protein synthesis.
**Why the Correct Answer is Right**
The correct answer is related to the concept of nitrogen balance and protein synthesis. When the diet contains a balanced mix of essential amino acids, the body can synthesize proteins efficiently and maintain a positive nitrogen balance. This is achieved through the action of enzymes such as glutamyl transferase, which catalyzes the transfer of glutamate to other amino acids, facilitating protein synthesis. The presence of a balanced mix of essential amino acids also stimulates the release of insulin and growth hormone, which further promotes protein synthesis.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not directly relate to the concept of overcoming limiting amino acids in the diet.
**Option B:** This option is incorrect because it refers to a different aspect of nutrition, specifically the concept of calories and energy balance, rather than protein synthesis.
**Clinical Pearl / High-Yield Fact**
A balanced diet that includes a mix of essential amino acids can help to promote protein synthesis and maintain a positive nitrogen balance, which is essential for wound healing, muscle growth, and overall health.
**Correct Answer: B. Branched-Chain Amino Acids (BCAAs) like Leucine are known to stimulate protein synthesis by activating the mTOR pathway.**