**Core Concept**
The one carbon pool refers to a group of biochemical reactions that transfer one carbon units, which are essential for the synthesis of purines, thymidine, and other biomolecules. This pool is crucial for the synthesis of nucleic acids and the maintenance of DNA integrity.
**Why the Correct Answer is Right**
The correct answer is involved in the one carbon pool through the action of the enzyme methionine synthase. This enzyme catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine, resulting in the formation of methionine. Methionine is then converted to S-adenosylmethionine (SAMe), which is a key donor of methyl groups in various biochemical reactions. The one carbon pool is also linked to the metabolism of folate, which is essential for the synthesis of purines and thymidine.
**Why Each Wrong Option is Incorrect**
**Option A:** This amino acid is involved in protein synthesis and is not directly related to the one carbon pool.
**Option B:** This amino acid is involved in the synthesis of glutathione, but it is not directly involved in the one carbon pool.
**Option C:** This amino acid is involved in the urea cycle and is not directly related to the one carbon pool.
**Clinical Pearl / High-Yield Fact**
Methionine synthase deficiency can lead to homocystinuria, a condition characterized by elevated levels of homocysteine in the blood. This condition can increase the risk of thrombosis and atherosclerosis.
**Correct Answer: C. Methionine**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.