Pharmacology Amiloride differs from spironolactone in that: A It has greater natriuretic action B Its diuretic action is more in the presence of conditions with elevated aldosterone levels C It acts from the luminal membrane side of the collecting duct cells D It can cause hypokalemia on long term use 💡 Explanation Amiloride differs from spironolactone in that: ✓ Correct Answer: C. It acts from the luminal membrane side of the collecting duct cells