Amiloride can cause hyperkalemia due to its action on:
Correct Answer: Sodium channel
Description: Ans. B. Sodium channelAmiloride and triamterene are K+ sparing diuretic, they act by inhibiting epithelial Na+ channel. When they inhibit the sodium channel, there is no generation of electrical gradient and thus potassium and hydrogen are not excreted. They may be responsible for hyperkalemia.
Category:
Pharmacology
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