**Core Concept**
Sjogren syndrome is a chronic autoimmune disorder characterized by lymphocytic infiltration and destruction of the exocrine glands, particularly the salivary and lacrimal glands. This leads to symptoms such as dry mouth (xerostomia) and dry eyes (xerophthalmia). The condition can also affect other organs, including the skin, joints, lungs, and kidneys.

**Why the Correct Answer is Right**
The correct answer is determined by identifying the feature that is NOT characteristic of Sjogren syndrome. The hallmark features of Sjogren syndrome include lymphocytic infiltration, glandular destruction, and exocrine gland dysfunction. These are typically accompanied by symptoms such as dry mouth and dry eyes.

**Why Each Wrong Option is Incorrect**
**Option A:**
* This option is incorrect because hypergammaglobulinemia is a feature of Sjogren syndrome, reflecting the underlying autoimmune process.

**Option B:**
* This option is incorrect because lymphocytic infiltration is a hallmark feature of Sjogren syndrome, particularly in the salivary and lacrimal glands.

**Option C:**
* This option is incorrect because glandular destruction, particularly of the exocrine glands, is a characteristic feature of Sjogren syndrome.

**Clinical Pearl / High-Yield Fact**
A key feature of Sjogren syndrome is the presence of anti-SSA/Ro and anti-SSB/La antibodies, which can be detected in the serum of affected individuals. These antibodies are highly specific for the diagnosis of Sjogren syndrome and can be used to distinguish it from other autoimmune conditions.

**Correct Answer: D.**