All the following are true about HIV infection except:
Correct Answer: Increased release of acid labile interferon
Description: Ans. (c) Increased release of acid labile interferon Infected T-4 cells do not appear to release normal amount of IL-2, IFNy and other lymphokines. y Interferon is acid stable in contrast to other interferons. Immunological abnormalities in HIV infection I. Features that characterize AIDS Lymphopenia Selective T cell deficiency -- Reduction in number of T4 (CD4) cells, Inversion of T4: T8 ratio. Decreased delayed hypersensitivity on skin testing Hypergammaglobulinemia -- predominantly IgG and IgA; and IgM also in children. Polyclonal activation of B cells and increased spontaneous secretion of lg. II. Other consistently observed features Decreased in vitro lymphocyte proliferative response to mitogens and antigens. Decreased cytotoxic response by T cells and NK cells Decreased antibody response to new antigens. Altered monocyte/macrophage function. Elevated levels of immune complexes in serum.
Category:
Microbiology
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