**Question:** All the following are features of Alzheimer's disease except:

A. Cognitive decline
B. Memory loss
C. Language impairment
D. Psychosis

**Core Concept:** Alzheimer's disease is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-beta plaques and tau protein tangles in the brain. It leads to cognitive decline, memory loss, and language impairment. Psychosis is a common complication of Alzheimer's disease, occurring in up to 70% of patients, but is not considered a primary feature.

**Why the Correct Answer is Right:** D. Psychosis is a common complication of Alzheimer's disease, occurring in up to 70% of patients. It is not a primary feature of Alzheimer's but rather a secondary manifestation due to the progressive destruction of the brain's structures involved in regulating mood, emotion, and behavior.

**Why Each Wrong Option is Incorrect:**

A. Cognitive decline: This is a primary feature of Alzheimer's disease and is characterized by progressive loss of memory, reasoning, and judgment abilities.
B. Memory loss: This is a central feature of Alzheimer's disease, with patients experiencing loss of short-term and long-term episodic memory, as well as other cognitive functions.
C. Language impairment: This is another primary feature of Alzheimer's disease, leading to difficulties in speech, comprehension, and writing.

**Clinical Pearl:** Psychosis in Alzheimer's disease is often triggered by stressors or infections and can be managed with antipsychotic drugs cautiously, considering the potential side effects and the patient's overall clinical condition.

**Correct Answer:** D. Psychosis

**Core Concept:** Psychosis is a common complication of Alzheimer's disease, occurring in up to 70% of patients. It is not a primary feature but rather a secondary manifestation due to the progressive destruction of the brain's structures involved in regulating mood, emotion, and behavior.

**Why Each Wrong Option is Incorrect:**

A. Cognitive decline: This is a primary feature of Alzheimer's disease, representing progressive loss of memory, reasoning, and judgment abilities.
B. Memory loss: Memory loss is a central feature of Alzheimer's disease, affecting short-term and long-term episodic memory, as well as other cognitive functions.
C. Language impairment: Language impairment is another primary feature of Alzheimer's disease, resulting in difficulties in speech, comprehension, and writing.

**Clinical Pearl:** Psychosis in Alzheimer's disease is often triggered by stressors or infections and can be managed with antipsychotic drugs cautiously, considering the potential side effects and the patient's overall clinical condition.