All the following about drug induced SLE are true except
Correct Answer: More common in females
Description: Ans. (a) More common in females(Ref: Robbins 9th/pg 218; 8th/pg 213)Drug-Induced LupusIt is a syndrome of positive ANA associated with symptoms such as fever, malaise, arthritis or intense arthralgias/myalgias, serositis, and/or rash.It appears during therapy with certain medications like antiarrhythmics procainamide, disopyramide, and propafenone; antihypertensive hydralazine; antithyroid propylthiouracil; antipsychotics chlorpromazine and lithium; anticonvulsants carbamazepine and phenytoin; antibiotics isoniazid, minocycline & nitrofurantoin; antirheumatic sulfasalazine; diuretic hydrochlorothiazide;It is predominant in whites & has less female predilection than SLEIt rarely involves kidneys or brain, is rarely associated with anti-dsDNA, is commonly associated with antibodies to histonesIt usually resolves over several weeks after discontinuation of the offending medication.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now