Gynaecology & Obstetrics All of these are true about GnRH analogues used in treatment of endometriosis , EXCEPT? A Continuous administration causes downregulation of pituitary gonadotropins B The risk of osteoporosis decreases with prolonged use as the estrogen mediated osteoblastic action continues C Add back therapy includes estrogens D Discontinuation causes recurrence 💡 Explanation All of these are true about GnRH analogues used in treatment of endometriosis , EXCEPT? ✓ Correct Answer: B. The risk of osteoporosis decreases with prolonged use as the estrogen mediated osteoblastic action continues