All of the following take part in the pathogenesis of macular edema in diabetic retinopathy except –
Correct Answer: Retinal pigment epithelium dysfunction
Description: Etiopathogenis of diabetic retinopathy (including macular edema)
Following factors are important in development of diabetic microangiopathy, which is responsible for the development of retinopathy :-
Activation of protein kinase C
Oxidative stress
Increased production of growth factors, amongst which Vascular endothelial growth factor A (VEGF-A is the most important). Other factors are TGF - β, PDGF, EGF and IGF
Category:
Ophthalmology
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