Pharmacology All of the following statements are true regarding warfarin toxicity (skin necrosis) except: A Skin necrosis occurs during initiation of therapy B Most common sites are toes and tips of fingers C Decreased quantity of protein C D Decreased incidence of adverse effects if therapy with LMWH is started. 💡 Explanation All of the following statements are true regarding warfarin toxicity (skin necrosis) except: ✓ Correct Answer: B. Most common sites are toes and tips of fingers