All of the following statements are true regarding carbimazole as compared to propylthiouracil except?
Correct Answer: Carbimazole cross placenta less than propylthiouracil
Description: Propylthiouracil has less transfer across placenta, so is preferred in first trimester of pregnancy. Propey Carbimazole PTU Potency Plasma half life Frequency of dosing Plasma protein binding Transfer across placenta Peripheral conversion Hepatotoxicity High More Once a day High High No effect Absent Low Less Thrice a day Low Low Inhibits Present
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