Pharmacology All of the following statements about the use of spironolactone in CHF are true except: A It should be administered in low doses to prevent hyperkalemia B It affords prognostic benefit in severe heart failure over and above that afforded by ACE inhibitors C It helps to overcome the refractoriness to thiazides D It affords rapid symptomatic relief in CHF patients 💡 Explanation All of the following statements about the use of spironolactone in CHF are true except: ✓ Correct Answer: D. It affords rapid symptomatic relief in CHF patients