All of the following statements about nateglinide are true except ?

Correct Answer: It decreases insulin resistance
Description: Sulfonylureas, nateglinide and repaglinide act by inhibiting ATP sensitive K channels and thus resulting in the release of insulin. Like insulin, all of these drugs can cause hypoglycemia. However, nateglinide therapy produces fewer episodes of hypoglycemia as compared to other oral insulin secretagogue. Nateglinide and repaglinide are short-acting and thus can reduce post-prandial hyperglycemia.
Category: Pharmacology
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