Pharmacology All of the following statements about methotrexate are true EXCEPT: A It is cell cycle specific and kills cells in the S phase B Its toxicity primarily affects bone marrow and epithelial structures C Folic acid reverses its toxic effects D It is the drug of choice for choriocarcinoma 💡 Explanation All of the following statements about methotrexate are true EXCEPT: ✓ Correct Answer: C. Folic acid reverses its toxic effects