All of the following statements about Creutzfcldt-Jakob disease are true, EXCEPT
Correct Answer: Myoclonus is rarely seen
Description: (C) Myoclonus is rarely seen # Creutzfeldt-Jakob disease is a neurodegenerative disease caused by Prions> Myoclonus is seen in 90% of patients with Creutzfeldt - Jakob disease.> Prions are infectious proteinaceous material devoid of detectable amount of nucleic acids.> Characteristics of diseases caused by Prions - Diseases are confined to central nervous system Basic pathology is - Neurodegeneration - Spongiform encephalopathy> Presence of Amyloid plaques in brain Hosts shows no inflammatory response (Disease is almost always fatal)> Clinical features (Symptoms): Usually presents in middle ages Rapidly progressive dementia Myoclonic fasciculations (seen in 90%) Ataxia Somnolence> Characteristic EEC pattern - Paroxysms with high voltage and slow waves
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