All of the following statements about carbohydrate antigen are true, EXCEPT:
Correct Answer: Memory response is seen
Description: Carbohydrate C -Ag is found in the cell wall of streptococcus pneumoniae. It is independent of T cell response, so memory response is present in the carbohydrate C - Ag. Polysaccharides (carbohydrates) are less immunogenic than protein antigens, but are more antigenic than lipids & nucleic acids. Carbohydrate (Polysaccharide) antigens are T- cell independent. Their immune response does not require activation of T-cells. These antigens directly stimulate B-cells without processing by antigen presenting cells. There is no memory response. Ref: Ananthanarayanan & Paniker's textbook of microbiology 7th ed pg 81.
Category:
Microbiology
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