Pathology All of the following statement are true regarding panacinar emphysema, except: A It affects only bronchiole sparing the alveoli B It have tendency to occur more in lower zones and base of lung C It is associated with alpha-1 antitrypsin deficiency D It can cause clinically significant airflow obstruction 💡 Explanation All of the following statement are true regarding panacinar emphysema, except: ✓ Correct Answer: A. It affects only bronchiole sparing the alveoli