All of the following pathology indicates the most malignant phyllodes tumor, EXCEPT:
Correct Answer: Fibrosarcoma
Description: Most malignant phyllodes tumors contain liposarcomatous or rhabdomyosarcomatous elements rather than fibrosarcomatous elements Evaluation of the number of mitoses and the presence or absence of invasive foci at the tumor margins may help to identify a malignant tumor. Small phyllodes tumors are excised with a margin of normal-appearing breast tissue. When the diagnosis of a phyllodes tumor with suspicious malignant elements is made, re-excision of the biopsy site to ensure complete excision of the tumor with a 1-cm margin of normal-appearing breast tissue is indicated. Large phyllodes tumors may require mastectomy. Axillary dissection is not recommended because axillary lymph node metastases rarely occur. Ref: Hunt K.K., Newman L.A., Copeland E.M., Bland K.I. (2010). Chapter 17. The Breast. In F.C. Brunicardi, D.K. Andersen, T.R. Billiar, D.L. Dunn, J.G. Hunter, J.B. Matthews, R.E. Pollock (Eds), Schwaz's Principles of Surgery, 9e.
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