All of the following is used as antiemetic, EXCEPT:
Correct Answer: Alosetron
Description: Alosetron is a 5-HT3 antagonist that has been approved for the treatment of patients with severe IBS with diarrhea. Four other 5-HT3 antagonists (ondansetron, granisetron, dolasetron, and palonosetron) have been approved for the prevention and treatment of nausea and vomiting (see Antiemetics); however, their efficacy in the treatment of IBS has not been determined. The differences between these 5-HT3 antagonists that determine their pharmacodynamic effects have not been well studied Ref: Katzung 11th edition Chapter 60.
Category:
Pharmacology
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