All of the following immunosuppressives cause profound myelosuppression except:

Correct Answer: Cyclosporine
Description: Ciclosporin&;s main effect is to lower the activity of T-cells; it does so by calcineurin-phosphatase pathway.Unlike cytotoxic immunosuppressants, it is free of toxic effects on bone marrow and RE system as it doesn&;t act on cell cycle.(ref: KD Tripathi 6/e p839)
Category: Medicine
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