**Core Concept**
The question tests the student's knowledge of ototoxic medications, which are substances that can damage the inner ear or auditory nerve, leading to hearing loss.
**Why the Correct Answer is Right**
Certain medications can cause hearing loss by damaging the hair cells in the cochlea or by disrupting the normal functioning of the auditory nerve. This can occur through various mechanisms, including the inhibition of mitochondrial function, disruption of ion balance, or direct toxicity to the hair cells. Examples of such medications include aminoglycoside antibiotics, such as gentamicin and tobramycin, which can cause irreversible hearing loss.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the medication listed can indeed cause hearing loss. For example, gentamicin is known to be ototoxic and can cause irreversible hearing loss.
**Option B:** This option is incorrect because the medication listed can cause hearing loss. For instance, cisplatin is a chemotherapeutic agent that is known to be ototoxic and can cause hearing loss in some patients.
**Option C:** This option is incorrect because the medication listed can cause hearing loss. For example, streptomycin is an aminoglycoside antibiotic that is known to be ototoxic and can cause hearing loss.
**Clinical Pearl / High-Yield Fact**
It is essential to carefully monitor patients receiving ototoxic medications for any signs of hearing loss, such as tinnitus or difficulty hearing. Early detection and intervention can help minimize the risk of permanent hearing loss.
**Correct Answer:** D.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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