All of the following drugs are used for the treatment of urinary incontinence except –
Correct Answer: Ipratropium
Description: Ans. is 'b' i.e., Ipratropium o In human urinary bladder, M2 and M. receptors are expressed predominantly with the M3 subtype mediating direct activation of contraction. M2 receptor acts indirectly by inhibiting relaxation by norepinephrine and epinephrine. o Drugs used for urinary incontinence ? Selective M3 antagonists - Oxybutynin, Darifenacin, solifenacin, Tolterodine. Nonselective antagonist - Trospium, Propiverine. Tricyclic antidepressant - Imipramine.
Category:
Pharmacology
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