All of the following conditions are associated with systolic thrill in left 2nd and 3rd intercostal space, EXCEPT:

Correct Answer: Pink TOF
Description: Pink TOF is not commonly associated with a left upper parasternal systolic thrill. It is associated with a systolic thrill in second and third intercostal space. The physiology of TOF depends primarily on the severity of pulmonary stenosis and on the size of the VSD. Pink TOF is said to occur in patients with a large VSD and mild pulmonary stenosis. These patients are initially asymptomatic and gradually develop congestive hea failure over few weeks to months as the pulmonary vascular resistance falls and left to right shunt predominates. They are clinically similar to patients with an isolated large VSD. Ref: Congenital Hea Defects By Diego. F. Wyszynski, Pages 218-220
Category: Medicine
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