All of the following can cause osteoporosis, EXCEPT:
Correct Answer: Fluorosis
Description: Osteoporosis is a skeletal disorder characterized by a loss of bone osteoid resulting in reduced bone integrity, thereby increasing the risk of fractures. Most common causes of osteoporosis are aging, highdose coicosteroid, thyrotoxicosis, hyperparathyroidism, alcoholism, sex hormone deficiency, paicularly menopause in women, tobacco, etc. Osteoporosis is caused by a reduction and disarray of bone's microarchitectural organic collagenous matrix, which accounts for 40% of bone mass and provides tensile strength. Calcium hydroxyapetite and phosphate compounds, mineralize the collagenous bone matrix and account for 60% of bone mass and bone's compressive strength. It is usually asymptomatic until fractures occur. Patients present with backache of varying degrees of severity or spontaneous fracture or collapse of a veebra. Ref: Current Medical Diagnosis and Treatment, 2012, Chapter 26; Textbook Of Ohopaedics By Kotwal, Page 108
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